Aryna Sabalenka will begin her quest for a historic third consecutive Australian Open crown when the first Grand Slam of the year begins on Sunday.
The Belarusian world No 1 headlines the evening session on the main Rod Laver Arena in a potentially tricky encounter with 2017 US Open champion Sloane Stephens at 7:00 pm (0800 GMT).
Men's second seed Alexander Zverev rounds off the first night against the dangerous Lucas Pouille of France, who made the semifinals at Melbourne Park in 2019 before losing to eventual champion Novak Djokovic.
Olympic champion Zheng Qinwen of China has the honour of playing the first point of the tournament on centre court when the fifth seed faces Romania's 110th-ranked Anca Todoni at 11:30am (0030 GMT).
Sabalenka is aiming to become the first woman since Martina Hingis (1997-99) to win three consecutive Australian Opens.
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If she lifts the winner's Daphne Akhurst Memorial Cup again, Sabalenka will join a select group of Margaret Court, Evonne Goolagong, Steffi Graf, Monica Seles and Hingis as the only women to complete a Melbourne three-peat.
"I know that I have the possibility of joining legends by winning three times in a row," Sabalenka said.
"Hopefully by the end of this tournament I'll be able to put my name into history."
The Belarusian won the Brisbane International last week and accepts she is the woman to beat after the best season of her career in 2024, where she also won a maiden US Open.
"I like that feeling. That's what drives me and helps me to stay motivated because I know that I have a target on my back and I really like to have it," she said.
Germany's Zverev, at a career-high No 2 ranking, has eyes on Jannik Sinner and a first Grand Slam title after losing to Carlos Alcaraz in the final at Roland Garros last year.
"I think everybody knows what I'm chasing," he said.
"Going into a Grand Slam as the world No 2, you have to have the mindset of, I want to win the tournament."
The 22-year-old Zheng lost to Sabalenka in the Australian Open final a year ago.
But it heralded a breakthrough 2024 during which she beat Swiatek on her way to winning Paris Olympic gold and claimed three WTA titles.
Zheng believes she is closing the gap on Sabalenka, who also beat the Chinese player at the US Open and in front of her home crowd in the final at Wuhan in October.
"I think each time I play against her, the results are getting closer and closer, which is a positive thing," said Zheng, who did not play any warm-up events before Melbourne.
"I need to have this mentality to be a better player. I'm right now top five, but still far away from my goal."
Men's sixth seed Casper Ruud of Norway begins his challenge against Spain's world number 61 Jaume Munar in the second match on Rod Laver.