South Africa will be without strike bowler Kagiso Rabada for Tuesday's opening one-day international against England at Headingley, captain Temba Bavuma revealed ahead of the clash.
The 30-year-old is still recovering from an ankle injury suffered in Australia, where South Africa won a three-match ODI series last month.
Matthew Breetzke, who has started his ODI career with four consecutive scores of 50 or more, injured his hamstring in the second of the ODIs against Australia and also sits out the opening clash against England as a precautionary measure.
Teenage pace bowler Kwena Maphaka, 19, will also not play as Bavuma said his workload was being managed, but he could yet feature in the limited overs clashes in England.
The three ODIs are followed by three Twenty20 internationals.
The Proteas Men add England to their ODI hit list 😤🎯
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"Kwena is an exciting player; he is still probably on the raw side, but that makes him even more exciting. He is a bit more awkward to face than other lefties, and he may have a role to play in these weather conditions," Bavuma told a press conference on Monday.
Veteran pinch-hitter David Miller also misses out on the ODIs but is in the squad for the T20s.
He remains in contention for the 2027 World Cup squad, added Bavuma.
The 36-year-old has not played international cricket since the Champions Trophy in March and missed the tour to Australia because he was playing in the Hundred competition in England.
"Any international commitments that occurred during the Hundred, David wasn't available for. Unfortunately, he wasn't part of our build-up for the ODIs. But then with the T20 stuff, the Hundred is done, he'll fall back into the team," the South Africa captain explained.
"David's still within the mix in the ODI stuff," he added.
Team: Aiden Markram, Ryan Rickelton (wicketkeeper), Temba Bavuma (captain), Tony de Zorzi, Tristan Stubbs, Dewald Brevis, Wiaan Mulder, Corbin Bosch, Keshav Maharaj, Nandre Burger, Lungi Ngidi.