Massimo Calvelli will step down from his role as chief executive of the ATP in June, the men's professional tennis governing body announced on Friday.
The Italian has been in the job since being appointed in January 2020.
The ATP said chairman Andrea Gaudenzi would combine his current role with the post of CEO as the organisation looks for Calvelli's successor.
"It's been a privilege to serve as CEO of the ATP over the past five years," Calvelli said in an ATP statement.
"I'm proud of the progress we've made together and deeply thankful to the team I've worked alongside."
The early part of his tenure was marked by an upheaval of the schedule due to Covid.
"Calvelli played a pivotal role in guiding the organisation through the challenges of the global pandemic," the ATP said.
Under Calvelli, the ATP also signed a multi-year partnership with the Saudi sovereign wealth fund in February 2024.
A tennis union co-founded by Novak Djokovic last month announced a series of legal actions aimed at the sport's governing bodies, including the ATP.
The Professional Tennis Players' Association (PTPA) alleged that "systemic abuse", "anti-competitive practices" and "a blatant disregard for player health" were prominent in the sport.