Wrexham will host Tottenham in the FA Cup fifth round if the non-league side can beat Sheffield United in a fourth round replay.
Fifth-tier Wrexham, who are owned by Hollywood actors Ryan Reynolds and Rob McElhenney, were handed a potential blockbuster tie in Monday's draw for the last 16.
Wrexham were seconds away from a shock win against Sheffield United on Sunday before the Championship side snatched a 3-3 draw, with Reynolds watching at the Racecourse Ground.
John Egan scored a late equaliser for United and the teams will meet again at Bramall Lane for the right to meet Premier League Tottenham.
Manchester City, 1-0 winners over Arsenal on Friday, travel to second-tier Bristol City, for the first meeting of the sides since the League Cup semifinals in 2018.
Pep Guardiola's men won then and are among the favourites for this year's FA Cup, a trophy they last lifted in the 2018-19 season.
Manchester United will host West Ham, who won 2-0 at third tier Derby on Monday.
Stoke entertain Brighton, who knocked out holders Liverpool 2-1 on Sunday.
Leeds will travel to either Fulham or Sunderland, who drew 1-1at Craven Cottage on Saturday. Leicester welcome either Blackburn or Birmingham.
Here is your #EmiratesFACup fifth round draw ??
— Emirates FA Cup (@EmiratesFACup) January 30, 2023
Which tie are you most looking forward to?
FA CUP FIFTH-ROUND DRAW
Southampton v Luton Town or Grimsby Town
Leicester City v Blackburn Rovers or Birmingham City
Stoke City v Brighton & Hove Albion
Wrexham or Sheffield United v Tottenham
Fulham or Sunderland v Leeds United
Bristol City v Manchester City
Manchester United v West Ham United
Ipswich Town or Burnley v Sheffield Wednesday or Fleetwood Town
Ties will take place in the week commencing February 27