Marseille suffered a late collapse and blew a two-goal lead to draw 2-2 at Paris FC in Ligue 1 on Saturday with the pain still fresh from their excruciating Champions League exit.
Mason Greenwood converted a first-half penalty for his league-best 13th goal of the season and set up Pierre-Emerick Aubameyang to double Marseille's lead early in the second half.
However, three days after crashing out of Europe in improbable fashion, Marseille came unstuck again as Jonathan Ikone's header brought Paris FC back into the game and Ilan Kebbal levelled with an injury-time spot-kick.
Marseille lost 3-0 at Club Brugge on Wednesday but it took a last-gasp header from Benfica's goalkeeper in a win over Real Madrid to knock Roberto De Zerbi's side out of the competition.
De Zerbi dismissed reports that he was stepping down in the wake of the defeat in Belgium after he missed a training session the next day.
The Italian said he had held talks with club officials to find the best way to move on from the Champions League disappointment, but the nature of Marseille's latest setback will only add to the unease at the Velodrome.
Lens moved back above Paris Saint-Germain into top spot on Friday after a Ruben Aguilar goal secured a 1-0 win at home to struggling Le Havre.
Luis Enrique's team will be able to reclaim first place by avoiding defeat away to Strasbourg on Sunday.