PSG moved to 55 points, 12 clear of second-placed Brest, who host Le Havre on Sunday. Monaco, still winless at home this year, remain third with 42 points.
Despite the visitors dominating possession, Monaco came closest to opening the scoring during the first half, with PSG goalkeeper Gianluigi Donnarumma keeping the hosts at bay.
PSG looked more dangerous in the second half, but Bradley Barcola and Vitinha could not find a way past keeper Radoslaw Majecki. PSG next play at Real Sociedad in the second leg of their Champions League last-16 tie on Tuesday, where they hold a 2-0 lead.