Australian Remy Gardner will replace injured MotoGP wild card Cal Crutchlow at the Briton's home grand prix next month, Yamaha said on Monday.
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Gardner, 26-year-old son of 1987 world champion Wayne, was also a stand-in for Yamaha's injured Spaniard Alex Rins in Germany on July 7.
Crutchlow, who retired from fulltime racing at the end of the 2020 season, would have been the only British rider in the top category at Silverstone but was forced to withdraw due to a hand injury.
"I had surgery on my hand two months ago, and the recovery has not gone as expected at all, leading to a further surgery and complications," the 38-year-old team test rider said.
"It is important to let my hand heal fully before trying to ride the MotoGP bike."
Rins is expected to have made a full recovery by the time of the race at Silverstone.