Alaves beat 10-man visitors Getafe 3-0 on Saturday as LaLiga's 2026/27 season began in Vitoria.
Kiko Femenia's red card late in the first half for a high lunge set Getafe back and Nahuel Tenaglia nodded home the opener for the hosts after 73 minutes.
Former Real Madrid striker Mariano curled home a fine second from the edge of the box in stoppage time as Quique Sanchez Flores's team got off to a winning start.
Mikel Rodriguez smashed home the third after being teed up by Mariano as Getafe crumbled during added time.
Later Saturday, Sevilla host Rayo Vallecano, while on Sunday Villarreal visit promoted side Racing Santander, among other games.
Atletico Madrid start their season at home against Malaga on Wednesday.
Jose Mourinho's Real Madrid are not in action until next weekend, visiting Espanyol on August 22, while champions Barcelona travel to face Elche on August 23.