Adama City caused a huge upset on Friday when they beat St George 2-1 while Hadiya Hossana secured a 2-0 win over Hambericho.
Adama came out firing and they were quickly out of the gates in the sixth minute when Mussie Kiros scored.
St George piled on the pressure through the rest of the first half but Adama held on to their 1-0 lead at the break.
Adama doubled their advantage in the 54th minute with Biniam Ayiten on target for 2-0.
St George pulled a goal back on 77 minutes through Tamirat Eyasu, but it was too little, too late as Adama held on for a famous win, and a jump to sixth place.
St George remain in second place behind Mekelakeya with the possibility that CBE will overtake them with a win.
Hadiya Hossana piled more misery on Hambericho's season with two second-half goals.
Hambericho looked to be on to something when they managed to hold Hadiya to a goalless first half.
However, their resistance was broken in the 65th minute when Temesgen Birhanu gave Hadiya a 1-0 lead.
Dawa Hotessa made it 2-0 in the 87th minute, securing a win that confines Hambericho to real relegation worries but moves Hadiya up three places to eighth on the log.