Ismaila Sarr scored twice as Crystal Palace reached the Conference League quarterfinals on Thursday with a 2-1 extra-time victory over AEK Larnaca in Cyprus, winning by the same score on aggregate.
Palace will face two-time Conference League runners-up Fiorentina in the last eight after the Italian club won 2-1 at Rakow Czestochowa in Poland, completing a 4-2 aggregate success.
The Eagles have endured a stop-start season, hit by the departure of centre-back Marc Guehi to Manchester City and the announcement that manager Oliver Glasner will leave at the end of the campaign.
But the English club remain in contention to add to their first ever major trophy, the FA Cup won last season, in their maiden European campaign.
"It's a huge achievement," Glasner told TNT Sports.
"We are looking forward to really make the best of these three weeks because our next competitive game is against Fiorentina at Selhurst Park."
Palace named a strong side for the last-16 second leg after two wins in four matches in recent weeks eased their Premier League relegation fears.
The visitors took a 13th-minute lead when Sarr was played in behind by Adam Wharton's deflected pass.
The Senegal winger kept his cool to round home goalkeeper Zlatan Alomerovic, who had advanced out of his area, and roll the ball into an empty net.
Sarr thought he had doubled the lead shortly afterwards but was flagged offside.
Larnarca managed to stay in the tie despite prolonged Palace pressure, though, and levelled 18 minutes into the second half through Enric Saborit's header.
The Spanish left-back was then sent off in the 73rd minute after receiving a second yellow card for a foul on Sarr, but the hosts held on to force extra time.
The Cypriots could not keep Palace at bay with 10 men until penalties, as Sarr fired home in the 99th minute from Daichi Kamada's pullback after a short corner.
It was Palace who looked more likely to score the game's fourth goal, as Sarr rattled the crossbar and then Jorgen Strand Larsen headed against the post, with the Dane and Jean-Philippe Mateta somehow contriving to fail put the rebound in between them.
Larnaca defender Petros Ioannou was dismissed late on for a foul on Mateta, but Palace still had to survive a nervy late set-piece to avoid a shoot-out.
STRASBOURG INTO QUARTERS
Strasbourg needed a 71st-minute goal from Valentin Barco to win 2-1 on aggregate against Croatians Rijeka and reach the quarterfinals of a major continental tournament for the first time since the 1979-80 European Cup.
The away team had drawn level in the tie through Toni Fruk midway through the first half.
Gary O'Neil's Strasbourg will next face Mainz who saw off Czechs Sigma Olomouc 2-0 in Germany, winning by the same score on aggregate.
AZ Alkmaar thumped Sparta Prague in the Czech capital 4-0, 6-1 on aggregate, as Troy Parrott scored his 10th Conference League goal of the season.
The Dutch club will next face Shakhtar Donetsk, while Rayo Vallecano will take on AEK Athens for a semifinal berth.