This season is the fourth time Atlético Madrid have lost the first leg of a UEFA Champions League knockout tie away from home – Diego Simeone’s side have progressed on two of the three previous occasions, however, eliminating Barcelona in 2015-16 (3-2 on aggregate) and Bayer Leverkusen in 2014-15 (1-1 on aggregate, progressing in a penalty shootout).
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This will be Manchester City’s first every away game against Atlético Madrid in European competition – the Citizens have won just three of their previous 11 away games against Spanish opponents (D1 L7), however one of those came on their most recent such trip under Pep Guardiola (2-1 v Real Madrid in February 2020).
After a run of nine victories in 10 home games between November 2017 and October 2020, Atlético Madrid are winless in their last seven home games in the UEFA Champions League (D4 L3) - their last win in the competition on home soil came in October 2020 (3-2 v RB Salzburg).
Manchester City boss Pep Guardiola has faced Atletico Madrid away from home on six previous occasions as a manager (W3 D3), with the most recent of those being a 0-1 defeat in the UEFA Champions League while in charge of Bayern Munich in 2015-16. This will be Guardiola’s first away game at the Wanda Metropolitano.
Atlético Madrid failed to attempt a shot in the first leg against Manchester City. Since 2003-04, the fewest shots recorded by a team across two legs of a UEFA Champions League knockout tie is four, by Shakhtar Donetsk against Bayern Munich in 2014-15. The only team to have failed to record a shot on target across two legs in this period was Deportivo La Coruña in the 2003-04 semi-finals against FC Porto.
This will be Manchester City’s 100th game in the UEFA Champions League – the Citizens have won 55 of their first 99, which is already the most by an English side through a century of games in the competition. Overall, only Real Madrid have won more of their first 100 games in the UEFA Champions League (57).
Atlético Madrid striker Antoine Griezmann has scored 29 goals in his career in the UEFA Champions League – should he score in this game, he would overtake David Trezeguet (29) for the fourth-most goals by a French player in the competition, trailing only Karim Benzema (82, as of the first leg), Thierry Henry (50) and Kylian Mbappé (33).
Manchester City's Riyad Mahrez has scored six goals across his last six away games in the UEFA Champions League. The Algerian has scored in three consecutive away games in the knockout stages of the competition; should he score in this match, only Cristiano Ronaldo will have scored in more such games consecutively (6 - 2013-2015).
Antoine Griezmann has been directly involved in 67% of Atlético Madrid’s goals in the UEFA Champions League this season (6/9 – four goals, two assists); the highest ratio of any player for his team among the eight quarter-finalists in 2021-22.
João Cancelo has been directly involved in five goals for Manchester City in the UEFA Champions League this season (two goals, three assists); the joint-most by a full back in one of Pep Guardiola’s teams in a single campaign in the competition, along with Dani Alves in 2010-11 (also two goals, three assists).