Mekelakeya's quest to go top of the Ethiopia Premier League log came to fruition despite being held to a goalless draw by Fasil Kenema on Thursday.
Mekelakeya move top of the table by one point ahead of Ethiopia Nigd Bank having played a game more.
Fasil move up to fourth on 19 points, level with Bahir Dar who drop to fifth on goals difference.
A resurgent Shashemene City held Ethiopian Insurance to a 1-1 draw in the day's other fixture.
Both Week 12 fixtures at the Adama Science and Technology Stadium drew massive crowds.
Insurance and Shashemene played out a goalless first half, but 11 minutes into the second half Ethiopian Insurance got the breakthrough on 66 minutes courtesy of Wogene Gezahegn.
The 1-0 lead lasted all but for minutes before Shashemene produced an equalider in the 70th minute thanks to Abdulkadir Nasir.
The draw means another valuable point for Shashemene City, who with eight points are now only one point behind struggling Wolkite in 14th place and two points behind Ethiopian Insurance in 13th.