Spain coach Luis de la Fuente called up some fresh faces including Real Madrid defender Fran Garcia and Athletic Bilbao midfielder Oihan Sancet for upcoming Euro 2024 qualifiers.
La Roja face Scotland on October 12 and Norway on October 15 as they bid to secure qualification for the tournament in Germany next summer.
Garcia was part of the squad which triumphed in the Netherlands this year as Spain won the Nations League but has not yet made his debut, while Sancet is included for the first time.
The 23-year-old midfielder has been sent off twice this season in six LaLiga appearances for Athletic, scoring one goal against Alaves.
De la Fuente also selected Barcelona's teenage winger Lamine Yamal again. The 16-year-old became Spain's youngest ever player and goalscorer in September as they thrashed Georgia.
Scotland top Group A with 15 points from five games, including a 2- 0 win over Spain in March, with Spain second on nine points, having played one fewer match.
Spain squad
Goalkeepers: Unai Simon (Athletic Bilbao), Kepa Arrizabalaga (Real Madrid), David Raya (Arsenal/ENG)
Defenders: Dani Carvajal (Real Madrid), Jesus Navas (Sevilla), Robin Le Normand (Real Sociedad), David Garcia (Osasuna), Pau Torres (Aston Villa/ENG), Aymeric Laporte (Al Nassr/KSA), Alejandro Balde (Barcelona), Fran Garcia (Real Madrid)
Midfielders: Rodri Hernandez (Manchester City/ENG), Martin Zubimendi, Mikel Merino (Real Sociedad), Fabian Ruiz (Paris Saint-Germain/FRA), Gavi (Barcelona), Oihan Sancet (Athletic Bilbao)
Forwards: Alvaro Morata (Atletico Madrid), Joselu (Real Madrid), Nico Williams (Athletic Bilbao), Lamine Yamal, Ferran Torres (Barcelona), Yeremi Pino (Villarreal), Mikel Oyarzabal (Real Sociedad)