Five players including England forward Marcus Rashford and Argentina winger Alejandro Garnacho have informed Manchester United that they wish to explore a future away from the Premier League side, a club source said on Friday.
Brazilian midfielder Antony, Dutch defender Tyrell Malacia and England international Jadon Sancho are also looking to leave the club, the source added.
Rashford, who has made more than 400 senior appearances for United, has fallen out of favour with manager Ruben Amorim, played for Aston Villa on loan while United had their worst-ever Premier League campaign, finishing 15th in the standings.
Amorim had called Rashford's work rate into question, saying he would rather put a goalkeeper coach on the bench than a player not giving their all.
Rashford said he was feeling fitter and better since joining Villa, where he scored two goals in 10 league appearances.
United also failed to qualify for the Champions League as they lost the Europa League final 1-0 to Tottenham Hotspur. Garnacho, who was a late substitute in the final, voiced his displeasure on social media after the loss.
"Up until the final I played every round helping the team, and today I play 20 minutes, I don't know," he wrote in a post. "The final will influence (my decision) but the whole season, the situation of the club."
Sancho was on loan at Chelsea where he made 31 league appearances last season. Antony, who joined United from Ajax Amsterdam in 2022 for a reported initial transfer fee of more than $100 million, scored five goals in 17 LaLiga appearances on loan at Real Betis.
Malacia joined Dutch side PSV Eindhovenon loan in February.