Bayern Munich and Bayer Leverkusen will clash in the standout tie of the last 16 in the German Cup after the draw was made on Sunday.
Leverkusen won the tournament last season on their way to a domestic double, beating Kaiserslautern in the final.
Bayern have won the German Cup a record 20 times, the most recent in 2020.
LAST 16 DRAW (ties being played on 3 and 4 December)
Bayern Munich v Leverkusen
RB Leipzig v Eintracht Frankfurt
Wolfsburg v Hoffenheim
Werder Bremen v Darmstadt
Karlsruhe v Augsburg
Regensburg v Stuttgart
Cologne v Hertha Berlin
Bielefeld v Freiburg