England suffered a setback on the eve of their Six Nations opener against Wales after Immanuel Feyi-Waboso was ruled out with a leg muscle injury.
The 23-year-old Exeter wing, who has scored seven tries in just 13 Tests, failed to finish Thursday's training session and England scrum coach Tom Harrison confirmed Friday that Feyi-Waboso will miss the match at Twickenham.
Feyi-Waboso's place on the right wing on Saturday will be taken by Tom Roebuck, making his first England appearance since starting against New Zealand in November following a toe problem.
Revised England team to play Wales (15-1)
Freddie Steward; Tom Roebuck, Tommy Freeman, Fraser Dingwall, Henry Arundell; George Ford, Alex Mitchell; Ben Earl, Sam Underhill, Guy Pepper; Ollie Chessum, Alex Coles; Joe Heyes, Jamie George (capt), Ellis Genge Replacements: Luke Cowan-Dickie, Bevan Rodd, Trevor Davison, Maro Itoje, Tom Curry, Henry Pollock, Ben Spencer, Marcus Smith Coach: Steve Borthwick (ENG)