England were forced into a late change to their starting line-up for the Six Nations clash against Italy in Rome after back rower Tom Curry limped out of the warm-up on Saturday.
Sam Underhill was promoted from the bench to start at flanker, with Chandler Cunningham-South coming in as a replacement.
Italy are bidding for a first ever victory over England after a run of 32 straight defeats.
Teams (15-1):
Italy
Lorenzo Pani; Louis Lynagh, Juan Ignacio Brex, Tommaso Menoncello, Monty Ioane; Paolo Garbisi, Alessandro Garbisi; Lorenzo Cannone, Manuel Zuliani, Michele Lamaro (capt); Andrea Zambonin, Niccolo Cannone; Simone Ferrari, Giacomo Nicotera, Danilo Fischetti
Replacements: Tommaso Di Bartolomeo, Mirco Spagnolo, Muhamed Hasa, Federico Ruzza, Riccardo Favretto, Alessandro Fusco, Leonardo Marin, Tommaso Allan
Coach: Gonzalo Quesada (ARG)
England
Elliot Daly; Tom Roebuck, Tommy Freeman, Seb Atkinson, Cadan Murley; Fin Smith, Ben Spencer; Ben Earl, Sam Underhill, Guy Pepper; Alex Coles, Maro Itoje (capt); Joe Heyes, Jamie George, Ellis Genge
Replacements: Luke Cowan-Dickie, Bevan Rodd, Trevor Davison, Ollie Chessum, Chandler Cunningham-South, Henry Pollock, Jack van Poortvliet, Marcus Smith
Coach: Steve Borthwick (ENG)
Referee: Luc Ramos (FRA)