France's record try scorer Damian Penaud will miss the rest of the Nations Championship due to a calf injury, the French Rugby Federation (FFR) announced on Monday.
Winger Penaud was replaced at halftime of Saturday's campaign-opening loss to New Zealand due to the issue, as he made his first test appearance since November.
The 29-year-old will be sidelined for games against Australia in Brisbane on Saturday and Japan in Tokyo on July 18.
Penaud scored his 41st test try after just two minutes in Christchurch, having been dropped from Les Bleus' successful Six Nations campaign earlier this year.
He was replaced by flyhalf Antoine Hastoy as Fabien Galthie reshuffled his back-line.
The FFR did not announce a replacement for Penaud in the squad, with specialist newspaper Midi Olympique claiming on Monday that starting flyhalf Matthieu Jalibert could move to fullback with Toulouse's Romain Ntamack taking over the No 10 shirt.