Ireland limited the injury damage from last weekend's bruising victory in Edinburgh and made just three changes as they seek to complete a Six Nations Gram Slam with victory over England in Dublin on Saturday.
No 8 Caelan Doris and hooker Dan Sheehan, two of the five Irish players who left the field injured against Scotland and who have been among Ireland's best players all campaign, are fit enough to start.
Centre Garry Ringrose and lock Iain Henderson were already ruled out but the return of fit-again Robbie Henshaw, starting his first game of the championship, softens the blow of losing the increasingly influential Ringrose.
Ryan Baird comes in at second row, with Leinster teammate Jamison Gibson-Park the other change as he returns to make his first start of the year to bring the kind of high tempo at scrumhalf England struggled with in last week's 53-10 thrashing by France.
While a draw at the Aviva Stadium will be enough to win the title, Ireland will want to underline their status as the world's top-ranked side with a clean sweep of victories heading into September's World Cup.
Amid the St Patrick's weekend festivities, it is also an opportunity to complete a Grand Slam on home soil for the first time in 75 years, having clinched the two secured since then in Cardiff in 2009 and London in 2018.
Ireland team: 15. Hugo Keenan (Leinster) 29 caps, 14. Mack Hansen (Connacht) 13 caps, 13. Robbie Henshaw (Leinster) 61 caps, 12. Bundee Aki (Connacht) 45 caps, 11. James Lowe (Leinster) 19 caps, 10. Johnny Sexton (Leinster) 112 caps (captain), 9. Jamison Gibson-Park (Leinster) 24 caps, 8. Caelan Doris (Leinster) 27 caps8. Caelan Doris (Leinster) 27 caps, 7. Josh van der Flier (Leinster) 49 caps, 6. Peter O'Mahony (Munster) 93 caps, 5. James Ryan (Leinster) 52 caps, 4. Ryan Baird (Leinster) 10 caps, 3. Tadhg Furlong (Leinster) 64 caps, 2. Dan Sheehan (Leinster) 16 caps, 1. Andrew Porter (Leinster) 52 caps
Replacements: 16. Rob Herring (Ulster) 33 caps, 17. Cian Healy (Leinster) 122 caps, 18. Tom O'Toole (Ulster) 8 caps, 19. Kieran Treadwell (Ulster) 10 caps, 20. Jack Conan (Leinster) 37 caps, 21. Conor Murray (Munster) 104 caps, 22. Ross Byrne (Leinster) 18 caps, 23. Jimmy O’Brien (Leinster) 4 caps